ORAL REHYDRATION SOLUTIONS FORMULAS
Gastrointestinal diseases with diarrheal complications are one of the main causes of morbidity and mortality in the world. Oral rehydration therapy and the formulation of oral rehydration salts were proposed in the late 1970s by WHO-UNICEF to combat the consequences of diarrheal diseases, and they agreed to promote a single solution with an osmolarity of 330 Mmol/l.
During the 90’s great advances have been made using this type of solution, helping to avoid more than 1 million annual deaths in children under 5 years of age. Subsequently, the ESPGHAM (European Society of Gastroenterology, Hepatology and Pediatric Nutrition) recommended a new improved formula with an osmolarity of between 200 and 250 mmol / l, since the oral rehydration salts with reduced osmolarity produce an optimal absorption of water ensuring an adequate replacement of sodium, potassium and bicarbonate. In addition, they also contain chlorine, bases and the potassium necessary, since significant amounts of these elements are lost in diarrheal stools.